Appropriate design and operation of both the storage and distribution systems is critical to the success of a bio pharmaceutical or life science water system. There are considerable numbers of systems designs for storage and distribution. The differences in these designs are directly correlated to the user requirements and the manufacturing requirements.
This provides an overview of common storage and distribution configurations, noting advantages and disadvantages of each alternative. Comparisons are provided for the alternatives and a decision flow chart is provided to help decide which alternative system best suits the operating requirements. Microbial considerations are discussed, as they apply to alternatives for continuous and periodic sanitization of storage and distribution. Typical system components also are discussed, along with alternative materials of construction, and common installation practices for storage and distribution systems.